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Dr. Todd Kuiken is a research associate for the Synthetic Biology Project at the Woodrow Wilson International Center for Scholars. He is collaborating with DIYbio.org on a project to ensure safety within the rapidly expanding community of amateur biologists.

If the “MAN” was just one man, dealing with new and exciting movements such as DIYbio would be rather easy. Unfortunately the “MAN” consists of numerous federal agencies ranging from the FBI to the EPA, all with different jurisdictions and oversight concerns. Add to that state and local agencies, neighborhood associations and your curious neighbor looking over the fence and the complexity of engaging with all of these groups becomes clear. The DIYbio community needs to take these agencies concerns seriously, as I think we are doing, and turn them into excitement over this new field of biology and the larger movement of citizen science as a whole.

As I began talking about DIYbio with various agencies a theme began to emerge amongst those who were tasked with “oversight”, for lack of a better word, of DIYbio. There was a general excitement about the community and the conversation frequently turned to “remember when science was fun”. While these various agencies have legitimate concerns surrounding the DIYbio movement, the conversations thus far have been positive and seem to be more about helping the movement move forward safely while encouraging more people to get “excited” about science again. By no means do I think this will be an easy task, but an exciting one as we begin to engage the larger public and move deeper into the caverns of regulations, local ordinances and address people’s fears and concerns about moving into the realm of citizen science. I believe strongly that if we follow three simple principles we can calm these fears and produce an environment where the DIYbio community can flourish and the larger citizen science movement can grow.

1. Turn concern into excitement
2. Make science fun again
3. If we engage them they will get it

I recently finished reading “The Radioactive Boy Scout” by Ken Silverstein, which describes the true story of a young man named David who over the course of his childhood became fascinated with DIYchemistry and by the time he graduated high school had designed and built a small nuclear reactor in his backyard (with a little help from a book published in 1960 called “The Golden Book of Chemistry”, long out of print and probably for good reason, but in short, has some pretty amazing experiments designed for the DIYer, including how to make chloroform!). In the end the EPA arrived, tore down his makeshift lab and turned his family’s suburban Detroit backyard into a Superfund site. This true story is an excellent example of how curiosity and people’s desire to explore science can both lead to pretty amazing accomplishments, from a technical standpoint, but can also carry with it serious safety concerns and potential over reaction by the federal government. I plan on writing future posts describing the significance of this story and how it relates to the DIYbio movement and the lessons we can take from it in order to better engage with the “MAN”.

Daniel Grushkin is a science journalist who has written for numerous national publications. He’s a cofounder of GenSpace, New York’s first community lab.

It’s been 25 years since Steven Levy came out with his seminal book Hackers, and we still can’t agree on a definition for them. Hackers are deft programmers and designers, they’re whiz kids who break into computer systems, they’re guys who wear leather overcoats à la The Matrix.

But let’s face it: in popular culture the term “hacking” is cool because it suggests a reversal of power. People who we thought were powerless turn out to be powerful, and those who we thought all-powerful end up weak (or at least silly). It’s cool when a 7-year-old blind boy figures out how to trick phone systems into giving him unlimited free calls by whistling at the right pitch. It’s cool when misfits take down a shady company by exposing their secrets (see Wikileaks or Lisbeth Salander).

It fulfills a fantasy we all have—that through moxie and smarts the little guy can upend the system. (I suspect that if you don’t consider yourself the little guy, then you don’t find it that cool.) But without the little guy on top, it doesn’t come off. Case in point, when China launches a cyber attack on the Pentagon, or when a government agency hacks into the little guy’s computer, it’s not that cool. Actually it’s scary.

I’m not sure who coined the term biohacker, but it sounds super- f#@ing cool. To others it sounds super-f#@ing scary. Unpack the term, and I’ll show you why.

You and I are the little guys in the biohacker scenario, but who’s the big guy? Where’s the reversal? At first you might think, ‘Oh, it’s the corporations and universities that spend billions to do what we’re doing on the cheap.’ I don’t think so. Though we may one day democratize science, if anything, we operate in parallel to these institutions.

I think the phrase biohacking suggests an even bigger “big guy,” at least it does to the popular press and culture-at-large. Hacking, at least in this context, assumes that the system has a purpose. When a hacker hacks a system he subverts its original purpose for his own. The little boy takes a system designed to trade telecommunication for money and makes it free. The misfit takes a system originally meant to secure information and turns it into a system that reveals information.

Similarly, for many when you use the term biohack, embedded in the notion is that biology has a purpose, that the designer (presumably God) created it to fulfill that purpose, just like the phone company or the security system. To hack it is to somehow subvert the design, and through it, supplant the designer (again, presumably God). Now granted, if you took an insider’s view of the term “hack” this would all seem preposterous. But look at this graphic from The Economist illustrating the creation of the first synthetic bacteria. That’s man playing the role of God in Michelangelo’s Sistine Chapel.

Credit: Economist, May 20th 2010

And you wonder why some of the public sees us as dangerous (parables like the Tower of Babel follow thereafter). At the same time, for others it’s also the reason why “biohacking” seems so cool (in this case, fantasies of creating a more logical world follow thereafter). Because, in a way, it’s the ultimate reversal of power: Hello God, here comes mankind.

Replace the theological with a Darwinian lens and the term again degrades into nonsense. Why? Because “purpose” is a term that doesn’t apply to evolution. A firefly shines bright not because it was designed to, but because it found utility in a string of mutations. Life is a MacGyver, “purpose” only comes after the biological change is made. So if you put the gene to shine bright in another organism (which we do), you are not subverting what some might call “divine will.” You are, however, throwing your own purpose into that life. Whether that organism finds utility in it is up to the organism (and the conditions you set).

Back to the term biohacker: I’m not saying you shouldn’t use it. Go ahead. But when you do, be aware of the associations you’re drumming up. Personally, it’s not worth it because the associations just don’t fit my worldview.

The suits think you can’t do biotech out in the garage. But the suits are wrong.

Meet Eri Gentry, queen of the bio-curious. In 2009, after the recession hit and every biotech company around was going belly up, Gentry went shopping. She picked up over a million dollars worth of lab equipment for $30,000 (around £20,000), installed it in her garage and invited her friends over to play. And her friends invited their friends and pretty soon Gentry was at the front end of the DIY biology movement.

Read the rest of the article at Wired:
http://www.wired.co.uk/news/archive/2010-07/15/eri-gentry-garage-biotech-revolution

More information about BioCurious at: http://www.biocurious.org