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DIY+iGEM

November 6, 2013

100ideas

iGEM + DIYBIO logos

The International Genetically Engineered Machines Competition (iGEM) is opening to DIY teams next year. It’s grown from a small experiment with 5 teams in 2004 to the largest community and conference of synthetic biologists in the world (with over 200 teams competing in 2013). I’m on the organizing committee for the new track – the “Community Labs” track – and I’m terrifically excited about the opportunity the iGEM competition provides for growing DIYbio.

I was asked to make the announcement at the recent iGEM World Jamboree, and below you can read a rough transcript of what I said. But if you just want to details, here they are:

DIY teams:

  • get the physical biobrick parts kit (DNA of over 1000 standard biological parts)
  • pay the same fees (~$3000 + $450 / person)
  • need two “PI” leaders (anyone can be one)
  • need a legally-recognized company to host the team (start your own, or ask a public lab to host your team; the two PIs need to be part of the team company)
  • compete amongst other teams in the DIY track to win the track prize
  • compete amongst all the teams for other prizes, including the GRAND PRIZE
  • can have members of any age
  • can be any size

Running an iGEM project is a big job, there’s no doubt. But if you’re up to it, you can use the competition as a powerful organizing tool for recruiting talented scientists, engineers, artists, and biohackers to work together and as a motivating force to solicit funds from many different local and national donors.

If you’re interested in spending six months building and designing your own biological system with synthetic biology, think about starting or joining an iGEM team in 2014.

I’m planning on starting a San Francisco team, and I’m going to recruit from the local biohacker scene, as well as from the local biotechs, big internet companies, and research labs. I see iGEM as a beautiful way to bring together really smart people to figure out and do DIY synthetic biology.

For more info, look on the diybio@googlegroups.com list for iGEM threads or leave comments below. You can also email diy@igem.org if you have specific comments or questions for the organizers.

Good luck!
Mac


(I gave shortened version of this talk (7 min in) at the iGEM 2013 Jamboree, excited and out of breath after sprinting over from the middle of a judging meeting. Not the pomp and circumstance I was hoping for – but it is more fitting for DIY I think.)

Hi everyone. First, I want to applaud all your amazing work engineering and building biological systems here in iGEM. It’s simply amazing. So. I’m Mac Cowell and terrifically excited to announce a new iGEM track – the iGEM Community Labs track. But before I give you the details, I’d like to just talk for a moment about how iGEM and DIYbio relate from my perspective.

iGEM is an engine for innovation, like the scientific academy and the free market. But in addition to the accolades of scientific publishing and the economic rewards of the free markets, the real motive force that energizes synthetic biology innovation in iGEM is powered by a simple desire by the participants to “push the technology” as far as possible – and to HAVE FUN. This is an intrinsic and separate motivation but just as a valid and important as a wish to advance science or make millions.

Innovating for the sake of innovation itself is an incredibly powerful force, and it’s what excites me – and you – about the opportunity iGEM offers to “push the envelope” of biological technology.

The worldwide community of “amateur biologists”, biohackers, citizen scientists, or otherwise “non-institutional scientists” are motivated in the same way. They want to push the envelope of biological technology. They want to, in general, increase the power of an individual to understand biological systems – “to understand things” – and to prototype biological designs – *to build things*. They ask why the tools we use as biological engineers – protocols and equipment and organisms and genes – are the way they are, and perhaps not simpler, less expensive, or just easier.

Like iGEM, the worldwide biohacker community thinks outside the box and innovates for the sake of innovation.

I was once an iGEM participant – in 2005. Over the following years, the I was continually amazed by the innovation at the edges of synthetic biology that iGEM stimulated. And most surprising of all, it was being done by you – undergraduates. Not teams of PhDs working for academic fame. Not companies motivated by profits. By you iGEM youngsters, driven by the simple obsession of inventing something *new*.

So in 2008, inspired by the community of iGEM biohackers – those kids inventing for invention’s sake, pushing the boundaries of what’s possible with synthetic biology – I coined a phrase with my friend Jason Bobe in an attempt to name the community with similar ideals outside of iGEM. We named it “diybio”. That name was a pebble at the top of a mountain. And over the last 5 years, it seems to have caused a landslide. But the two of us just gave it it’s first little push.

But despite their fundamental alignment, the diybio & iGEM communities have not formally intersected – until now.

In 2014, DIY teams operating their own labs are invited to participate in iGEM. The fees will be the same as for other teams – roughly $3000 to register and $450 per participant going to the Jamboree. DIY teams will receive the part distribution and will compete with other DIY teams in the track, as well as being eligible for awards from the other iGEM tracks as well as the grand prize. In other words, a DIY team, like the teams in the other tracks, could be the ultimate winner of the competition. DIY teams are required to have two leaders – or “PIs” – who do not have to be accredited scientists, but who do need to be listed as managers or leaders of the company that runs the teams lab space.

If a team wants to form a new lab, that’s fine – they’ll just need to create an LLC or C-corp or other legal entity as an umbrella for their activities. Or they can ask members of an existing organization to act as the PIs of the team. Importantly, these PIs and the associated legal entity are what become responsible for the activities and behavior of the team – not the iGEM organization.

iGEM requires a large investment in time and money to participate, but its format as annual competition actually facilitates fundraising, recruitment, and general motivation to do something BIG. It provides a compelling vehicle to organize a team, a lab, and get a project done on time. Having observed the competition grow from 13 teams in 2005 to over 200 teams in 2013, I’ve noticed time after time how much easier it is for teams to raise money when they tell donors “we need this money to win! support us and the local community,” instead of “we need this money to do our science project – please support us and science!”.

In my opinion, the new DIY track could stimulate many new community labs and teams to form with great benefits to the diybio community.

Anyone can start a team, and for you, I have two critical suggestions. As the leader of the team, you’ll have two main jobs in the beginning, just like a CEO: 1) recruiting awesome teammates, and 2) raising money to support the team.

Start with recruitment first. Put together a talk or presentation about what iGEM is and why you’re excited about participating, then go to your local communities that might have awesome people interested in helping, and get them excited! Go to local biotech companies, research labs, retiree communities, schools, museums, hackathons, lightning talks, science nights, and any other venue you think might be a filter for smart, capable, motivated people interested in biohacking. You can use iGEM to build an amazing local team of talented scientists and engineers.

Once the team starts to come together, do the same roadshow at local businesses, asking for sponsorship. Tell them you’ll put their logo all over your tshirts and website etc. Try to get some grants from the city. Ask for $1000 from the awesomefoundation.org.

DIY iGEM teams in 2014 are a huge opportunity to build the strength and reach of DIYbio everywhere. I encourage you all to consider starting teams and using iGEM as a focal point for getting great people and real money involved in DIYbio.

More details about participating will be available at iGEM.org in 2014. In the meantime, please direct any questions or comments to diy@igem.org.

Get excited!
Mac Cowell

Funding Models for DIY biologists

December 14, 2012

Jason Bobe

Over at Nature’s SpotOn, Rayna Stamboliyska asks the question: “How do we make DIYBio sustainable?”

Check out her review of funding strategies in the DIYbio community to-date, including:

  • membership fees (e.g. Biocurious)
  • fee for service (e.g. workshops at Genspace)
  • grant funding (e.g. MadLab UK)
  • crowdfunding (e.g. Open PCR)
  • commercialization (e.g. Amplino)

Thanks Rayna!

Hardware: Algae microscope and cell-picker

Project
Hackteria XYCellPicker stage

Draft entry

Developer:

Urs Gaudenz AKA GaudiLab & HackteriaLab team

Date:

Rolling Development

Description:

A CD-ROM reading head for XY micro-positioning of a small glas capillary. The coil head is controlled using an arduino. The coils are directely connected to the PWM output pins. Picking head mounted on a larger XY-table (roboscope-style cam design, -ed.) for macro adjustments using the two stepper motors.

Design Files

Formal specs unavailable. But here’s a hackterish photo by way of illustration:
Hackterialab WebCamCellPicker diagram

Related Hardware:

roboscope xyz stage video

Previous Coverage:

- uncertain

Read more

Hardware: GoGoFuge

Project
GoGoFuge orthometric photo

Developer:

Keegan Cooke

Date:

18 Mar 2012

Description:

Case, display, and control electronics for dremelfuge-based centrifuge. Based on GoGoBoard. Created as part of Standford FabLabs at School program. Designed to convert into vortexer shaker with eccentric-axis tube holder and rubber bands. Instruction Manual.

Design Files

GoGoFuge laser-cutting vectors – wood (.cdr)
GoGoFuge laser-cutting vectors – acrylic (.cdr)
GoGoFuge GoGoBoard firmware (.gogo)
note: please visit the gogofuge manual page if the design files links are broken.
Hardware license statement unavailable.

Related Hardware:

Dremelfuge Classic

Previous Coverage:

Keegan Cooke diybio list announcement

Read more

Hardware: add a project

Project
diybio reveolution

Got a hardware project that should be listed at diybio.org/hardware? Please provide a link to more details in the comments below.

Hardware: Dremelfuge Classic

Project
Dremelfuge Classic attached to dremeltool

Developer:

Cathal Garvey

Date:

12/29/09

Description:

Design for mini-centrifuge rotor that fits onto a Dremel tool shaft. 6-tube capacity. 3D-printing suitable for manufacturing. Open-Source Hardware. Design files available at thingiverse.com, 3D prints available at Shapeways.com.

Cathal Garvey:“Intended basic applications of Dremelfuge include column purification (tested to work with miniprep columns) and bacterial/cell debris pelleting (under testing). With standard microcentrifuge tubes, the average rotary distance is 4cms.”

Design Files

thingiverse.com – License unknown

Related Hardware:

- Keegofuge

Previous Coverage:

DIY Centrifuge using Dremel Tool

Read more

BioArt Laboratories Grand Opening May 18 in Eindhoven

May 8, 2012

Jason Bobe

Very happy to add BioArt Laboratories to the /local page. They will be having their Grand Opening on May 18th in Eindhoven, The Netherlands.  Jalila wrote to say everyone is invited!

http://bioartlab.com/
https://www.facebook.com/BioArtLab

BioArt Laboratories
Achtseweg zuid 151
5651GW Eindhoven
The Netherlands

Flyer: Invitation to Opening of BioArt Laboratories (PDF)

diybio news aggregator

February 22, 2012

100ideas

news.diybio.org

If you drop by news.diybio.org, you’ll find a live aggregator of all sorts of diybio-related news feeds, updated in real-time.  We’re aggregating diybio-related blogs, twitter feeds, and email topics on the main diybio google group.

Here is the list (opml) of the diybio blogs our news aggregator follows. Please suggest additional blogs for us to follow in the comments

So – go check out the news: news.diybio.org!

The aggregator software is developed and maintained by Dan Choi and is loosely based on his boston-rubyists project – thanks, Dan!

MOAR BLOGZ!

Please add suggestions for additional blogs and twitter feeds to the comments below and we’ll add them to the news dashboard.

DIYbio News Round-up

January 16, 2012

Jason Bobe

The DIYbio community has been featured in several major news outlets recently.  Here is a round-up, with links to featured individuals and community labs:

Postcard Subscribers 1 Jan 2012

January 3, 2012

100ideas

diybio postcard subscribers - 01 Jan 2012

The community posted some great submissions (see them here) for the first diybio postcard “mini-newsletter”, providing a brief snapshot of activity over the last two months.

Over the next two weeks I’ll finish the layout, printing, and mailing of the cards, so they should hopefully be arriving in your mailbox around the end of January. The cards are going all over the world, to over 100 subscribers spanning six of the seven continents (aren’t there any diybiologists in Antarctica yet?).

Subscribe for free, learn more about the postcard project, or check out the entries for the first postcard.

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